Tfaily Lab team photo

Tfaily Lab · University of Arizona

Reading the molecular language of ecosystems

We study how organic matter, microbes, and climate shape each other. We use high resolution mass spectrometry, multi-omics, and AI to follow carbon from molecules to whole ecosystems, and to see how these changes reach human health.

150+

peer reviewed papers

Desert to permafrost

ecosystems we study

Earth to Mars

soils we explore

Molecules to models

how we connect the data

What we study

01

Organic matter dynamics

How organic matter changes in soil, water, and air, from deserts and peatlands to permafrost and rainforests.

02

Microbial drivers

How microbes control greenhouse gas release and carbon storage, on Earth and beyond.

03

Plant metabolic responses

How plants respond to stress, and what that means for ecosystem resilience and invasion.

04

New analytical tools

New methods and data pipelines that link molecules, microbes, and ecosystems.

05

Environment and human health

How pollutants such as polyaromatic hydrocarbons affect human metabolism and health.

06

Metabolomics and AI in ecology

Metabolomics and AI models that track biodiversity and predict ecosystem change.

07

Phages for climate

Using phages to lower methane release from thawing permafrost.

08

Phages for human health

Phage therapy to fight antibiotic resistant infections in burn wounds.

Abstract image with a van Krevelen style compound cloud, a mass spectrum, and a multi-omics network

From molecules to models

We measure thousands of molecules in a single sample. We link them to genes, microbes, and climate data. Then we build models and AI tools that predict how ecosystems will respond to change.

Our open source tools, MetaboDirect and MetaboTandem, help other labs do the same.

Join the lab

We welcome curious students, postdocs, and collaborators. Come work with us on soils, water, microbes, and data.